Oxford University Gene Medicine : Cystic Fibrosis Gene Therapy


Latest News Friday 16 March 2012: Funding has been secured for the UKCFGTC's clinical trial & research programme.

Welcome to the website of the Oxford University Gene Medicine Research Group. We are a University of Oxford research group based in the Nuffield Department of Clinical Laboratory Sciences at the John Radcliffe Hospital.

Our work is primarily focused on the development of a clinical gene therapy for the treatment of Cystic Fibrosis (CF) lung disease.

Together with colleagues at the University of Edinburgh and Imperial College London we form the UK Cystic Fibrosis Gene Therapy Consortium. The Consortium is funded solely by the UK Cystic Fibrosis Trust.

The Consortium is currently undertaking a series of clinical trials in CF patients, based on the research that the three sites have conducted over the past six years.

Learn about Cystic Fibrosis

Research Highlights

Recent Publications from our Group

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UK CFGTC

How the Consortium works/FAQs

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Centre for Molecular Medicine, Edinburgh
The Roslin Institute
Dep of Gene Therapy, Imperial

Milestones

GL67A/pGM169

The Run-in Study

Single Dose Clinical Trial

Multi Dose Clinical Trial

 

Our Research

Non-viral Vector Development

Aerosol Mediated Gene Delivery

Viral Vector Development

Taqman Core Facility

Cystic Fibrosis

History of CF

Discovery of the CFTR Gene

CFTR Protein Structure

CFTR Function

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Gene Therapy

Introduction to Gene Therapy

Other CF Gene Therapy Groups

Why use Gene Therapy for CF

Target Cells for CF Gene Therapy

Barriers for CF Gene Therapy

Clinical Trials

Gene Therapy Successes

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Gene Therapy Seminars

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